Category: Medicine

The cancer therapeutic implications of the Warburg effect.

Whereas normal human cells use a process named mitochondrial oxidative phosphorylation (MOP) to generate energy from glucose, some unicellular organisms (eg: microbes) use a different process called anaerobic glycolysis to reproduce as quickly as possible when nutrients are available. The Nobel laureate, Otto Warburg, noticed in 1924 that cancer cells metabolize glucose in a different…

Low carb diets. Useful as autoimmune disease treatment?

Inflammation is an immune physiological process that usually helps to control infections as well as in the subsequent repair of the affected tissue. Inflammasomes are multiproteic complexes expressed by the innate immune system cells whose activation induces the release of proinflammatory substances as interleukin-1. These multiproteic complexes are clinically-important because some autoimmune diseases express an…